In general, the more stable the conjugate base, the stronger the acid. Most acidic proton in the structure of Ascorbic Acid (Vitamin - YouTube Using the pKa table, determine a suitable reagent to deprotonate the following compounds. This content is for registered users only. Aldehyde and aromatic protons are not at all acidic (pKa values are above 40 not on our table). ROCO Acid-Base: Most acidic H - Reed College Download the PDF file of the pKa Table belowhere to work on the following problems. The lower the pKa of a Bronsted acid, the more easily it gives up its proton. Sulfuric acid is the strongest acid on our list with a pKa value of 10, so HSO4- is the weakest conjugate base. 11.10: Identifying Acidic Protons - Chemistry LibreTexts Conversely, acidity in the haloacids increases as we move down the column. PDF Chapter 3 Acids and Bases MechRocket. Effectively, the strong base competes so well for the proton that the compound remains protonated. Heres another way to think about it: the lone pair on an amide nitrogen is not available for bonding with a proton these two electrons are too comfortable being part of the delocalized pi-bonding system. By clicking Accept all cookies, you agree Stack Exchange can store cookies on your device and disclose information in accordance with our Cookie Policy. 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